Well it’s been exactly one week since I started my course of Roaccutane and it hasn’t been too bad. I’ve been taking one tablet in the morning and then another in the evening with a glass of milk. I had to invest in lip balm stuff called Blistex because my lips were starting to dry quite badly. I’m getting used to it now but my skin overall is starting to dry up. I had some minor headaches last weekend but they may or may not have been related. Other than that I haven’t had any major side affects.